Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Involvement of Articular Cartilage in a Linear Relaxation Process during Walking

Abstract

A KNEE joint consists essentially of a pair of articulating bone surfaces lined with cartilage; the latter is swollen with an aqueous solution of protein and salts and contained within a sac (synovial membrane). The solution to problems of friction and wear in the normal joint has attracted attention to the properties of the bearing material, articular cartilage—a composite macromolecular gel made up chiefly of collagen and various mucopolysaccharides, together with 70–80 per cent fluid. In several in vitro studies, articular cartilage has been separated from bone, cut into simple geometric shapes and subjected to compressive loading. It has been repeatedly observed1–4 that, after the application of load, cartilage expresses a portion of its fluid within between 20 and 60 min, at the end of which the weight of transferred fluid reaches a constant level (Fig. 1). When the load is removed, fluid gradually re-enters the cartilage and swells it; eventually, the fluid content returns to its original level3,4.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Lewis, P. R., and McCutchen, C. W., Nature, 184, 1285 (1959).

    Article  ADS  CAS  Google Scholar 

  2. McCutchen, C. W., Wear, 5, 1 (1962).

    Article  Google Scholar 

  3. Linn, F. C., and Sokoloff, L., Arthritis and Rheumatism, 8, 481 (1965).

    Article  CAS  Google Scholar 

  4. Edwards, J., in Lubrication and Wear in Living and Artificial Human Joints, 16 (Institution of Mechanical Engineers, London, 1967).

    Google Scholar 

  5. Radin, E. L., and Paul, I. L., Arthritis and Rheumatism, 13, 1 (1970).

    Article  Google Scholar 

  6. Sokoloff, L., The Biology of Degenerative Joint Disease (University of Chicago Press, 1969).

    Google Scholar 

  7. Yannas, I. V., and Lunn, A. C., J. Macromol. Sci.. Phys, B4 (3), 603 (1970) Yannas, I. V., Sung, N-H., and Lunn, A. C., J. Macromol. Sci. (in the press).

    Article  ADS  CAS  Google Scholar 

  8. Grieve, D. W., in Lubrication and Wear in Living and Artificial Human Joints, 150 (Institution of Mechanical Engineers, London, 1967).

    Google Scholar 

  9. Montgomery, S. R., in Lubrication and Wear in Living and Artificial Human Joints, 151 (Institute of Mechanical Engineers, London, 1967).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

YANNAS, I. Involvement of Articular Cartilage in a Linear Relaxation Process during Walking. Nature 227, 1358–1360 (1970). https://doi.org/10.1038/2271358b0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/2271358b0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing