Figure 3: How the release of cytochrome c from mitochondria contributes to apoptosis. | Nature

Figure 3: How the release of cytochrome c from mitochondria contributes to apoptosis.

From: Cell suicide for beginners

Figure 3

The released cytochrome c molecules bind to CED-4-like adaptor proteins. The adaptor proteins then aggregate and bind procaspase-9 molecules. The clustered procaspase-9 molecules activate one another, and the activated caspase-9 molecules then activate other procaspases, leading to apoptosis.

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