Abstract
An immunologically specific factor circulating in lymph and blood prevents the occurrence of lung metastases in rats with sarcomas growing in the leg. Removal of thoracic duct lymph causes such tumours to metastasize to the lung. This is due to the removal of a plasma factor and not of lymphocytes.
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PROCTOR, J., RUDENSTAM, C. & ALEXANDER, P. A Factor Preventing the Development of Lung Metastases in Rats with Sarcomas. Nature 242, 29–31 (1973). https://doi.org/10.1038/242029a0
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DOI: https://doi.org/10.1038/242029a0
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