Abstract
We have isolated a complementary DNA clone by screening a rat brain cDNA library for expression of kainate-gated ion channels in Xenopus oocytes. The cDNA encodes a single protein of relative molecular mass (Mr) 99,800 which on expression in oocytes forms a functional ion channel possessing the electrophysiological and pharmacological properties of the kainate subtype of the glutamate receptor family in the mammalian central nervous system.
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Hollmann, M., O'Shea-Greenfield, A., Rogers, S. et al. Cloning by functional expression of a member of the glutamate receptor family. Nature 342, 643–648 (1989). https://doi.org/10.1038/342643a0
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DOI: https://doi.org/10.1038/342643a0
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