Figure 2 | International Journal of Impotence Research

Figure 2

From: Role of oxidative stress and antioxidants in Peyronie's disease

Figure 2

Scheme suggesting role of oxidative stress and antioxidants involving NF-κB activation pathway leading to over expression of specific target genes and formation of Peyronie's plaques. The shaded boxes represent various penile compartments where these major cellular events are predominantly taking place. The potential sites of inhibitory effects of alpha-interferon and ROS scavengers are also shown in circles.

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