Embryonic stem cells can develop into many specialized cell types in culture dishes. It now seems that they can also generate primordial germ cells, which then go on to form sperm and eggs.
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Surani, M. How to make eggs and sperm. Nature 427, 106–107 (2004). https://doi.org/10.1038/427106a
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DOI: https://doi.org/10.1038/427106a