The vitamin-A metabolite retinoic acid normally favours immune tolerance in the gut. But in coeliac disease — an intestinal inflammatory disorder due to adverse reactivity to a dietary protein — it may do just the opposite. See Letter p.220
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Maynard, C., Weaver, C. Context is key in the gut. Nature 471, 169–170 (2011). https://doi.org/10.1038/471169a
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DOI: https://doi.org/10.1038/471169a