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Structural biology

Signalling from disordered proteins

Nature volume 498, pages 308–310 (2013)Cite this article

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The discovery that a disordered protein can transmit signals between two binding sites calls into question the idea that communication within proteins requires a specific structural pathway linking such sites. See Letter p.390

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Figure 1: The structural view of allostery.
Figure 2: The ensemble view of allostery.

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  1. Vincent J. Hilser is in the Departments of Biology and Biophysics, Johns Hopkins University, Baltimore, Maryland 21218, USA.,

    Vincent J. Hilser

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  1. Vincent J. Hilser
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Correspondence to Vincent J. Hilser.

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Hilser, V. Signalling from disordered proteins. Nature 498, 308–310 (2013). https://doi.org/10.1038/498308a

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