Table 2 Fst values for each SNP in the eight geographical regions

From: Haplotype tagging efficiency in worldwide populations in CTLA4 gene

  

Sub-Saharan Africa

North-Africa

Middle East

Europe

Central/South Asia

East Asia

Oceania

America

Global a

Global b

No. of populations

rs i.d.

7

3

3

10

8

6

2

5

44

 

−1765 T/C

rs11571315

0.007 (0.61)

−0.006 (0.30)

0.109 (0.24)

0.013 (0.34)

0.008 (0.30)

0.007 (0.63)

0.025 (0.26)

0.021 (0.54)

0.105

0.102

−1722 T/C

rs733618

0.025 (0.90)

−0.010 (0.94)

0.005 (0.87)

0.017 (0.96)

0.001 (0.88)

0.037 (0.64)

−0.008 (0.99)

0.103 (0.86)

0.108

0.095

−1661 A/G

rs4553808

0.036 (0.85)

0.003 (0.78)

−0.001 (0.83)

0.003 (0.84)

−0.016 (0.90)

0.088 (0.90)

−0.027 (0.84)

0.010 (0.98)

0.034

0.015

−1577 G/A

rs11571316

0.022 (0.90)

0.011 (0.57)

0.063 (0.46)

0.004 (0.49)

0.003 (0.40)

0.021 (0.71)

0.079 (0.45)

0.038 (0.54)

0.121

0.122

−658 C/T

rs11571317

0.000 (1.00)

0.033 (0.94)

0.051 (0.94)

0.018 (0.90)

−0.002 (0.98)

0.000 (1.00)

0.013 (0.98)

0.003 (1.00)

0.062

0.048

−319 C/T

rs5742909

−0.012 (1.00)

0.012 (0.97)

0.011 (0.92)

−0.014 (0.91)

−0.007 (0.95)

0.039 (0.92)

0.012 (0.99)

−0.002 (0.98)

0.028

0.022

+49 A/G

rs231775

0.081 (0.61)

−0.005 (0.72)

0.085 (0.77)

0.020 (0.72)

0.015 (0.70)

0.004 (0.36)

0.028 (0.71)

0.019 (0.50)

0.102

0.088

+6230 G/A

rs3087243

0.033 (0.90)

0.004 (0.57)

0.031 (0.42)

0.003 (0.46)

0.010 (0.37)

0.028 (0.71)

0.034 (0.45)

0.031 (0.58)

0.134

0.137

+6249 G/A

rs11571319

0.067 (0.76)

−0.003 (0.78)

−0.001 (0.88)

−0.005 (0.86)

−0.012 (0.91)

0.045 (0.92)

−0.027 (0.85)

0.010 (0.93)

0.034

0.019

+7092 A/G

rs231723

0.065 (0.66)

0.038 (0.71)

0.130 (0.55)

0.021 (0.73)

0.024 (0.68)

0.005 (0.36)

0.019 (0.64)

0.023 (0.48)

0.101

0.065

+7482 A/C

rs10197010

0.099 (0.76)

0.008 (0.72)

0.012 (0.79)

−0.004 (0.86)

−0.013 (0.87)

0.042 (0.90)

−0.027 (0.85)

0.026 (0.98)

0.037

0.017

+7982 G/A

rs231725

0.114 (0.64)

0.005 (0.74)

0.083 (0.88)

0.018 (0.76)

0.039 (0.77)

0.021 (0.46)

0.004 (0.75)

0.018 (0.52)

0.125

0.105

+8173 C/T

rs231726

0.160 (0.73)

0.001 (0.80)

0.076 (0.88)

0.024 (0.77)

0.032 (0.77)

0.017 (0.44)

−0.009 (0.74)

0.014 (0.52)

0.122

0.097

+10 242 T/G

rs11571302

0.049 (0.35)

0.001 (0.47)

0.004 (0.59)

−0.002 (0.60)

0.009 (0.63)

0.049 (0.32)

0.008 (0.60)

0.031 (0.42)

0.102

0.098

+10 717 G/A

rs7565213

0.041 (0.80)

0.005 (0.55)

0.010 (0.46)

0.004 (0.40)

0.007 (0.37)

0.058 (0.70)

0.008 (0.40)

0.031 (0.58)

0.104

0.098

+12 131 C/G

rs10932025

0.079 (0.76)

−0.005 (0.78)

0.025 (0.77)

−0.006 (0.83)

−0.014 (0.87)

0.042 (0.90)

−0.027 (0.85)

0.044 (0.98)

0.033

0.019

+12 310 T/C

rs11571297

0.052 (0.78)

0.004 (0.53)

0.004 (0.40)

0.003 (0.39)

0.010 (0.35)

0.049 (0.67)

0.008 (0.40)

0.031 (0.58)

0.101

0.095

Averagec

 

0.068

0.005

0.046

0.008

0.009

0.031

0.013

0.028

0.096e

0.085f

AMOVA P-valuesd

 

<0.001

NS

<0.001

NS

NS

<0.001

NS

0.047

<0.001

 
  1. In parentheses, median frequency of the ancestral allele (marked in bold in the first column).
  2. aGlobal comparison of all populations for each SNP.
  3. bGlobal comparison of the eight geographical groups for each SNP.
  4. cAverage Fst over all loci for each continental region.
  5. dAnalysis of the molecular variance (AMOVA). NS=not significant.
  6. eGlobal comparison of all populations for the average Fst over all loci.
  7. fGlobal comparison of the eight geographical groups for the average Fst over all loci.
Back to article page