Abstract
Objective:
Describe the incidence of catheter-related blood stream infection (CRBSI), following removal of peripherally inserted central venous catheters (PICC) in preterm infants.
Study Design:
A retrospective cohort study of infants <29 weeks gestational age with a PICC revealed 101 PICCs placed (2159 PICC days). Patients were hospitalized in a level III Neonatal Intensive Care Unit (NICU) between January 2002 and December 2003. χ2 analysis was performed.
Results:
One infection was detected after the removal of a PICC (1 per 202 days). Ten infants had a CRBSI attributed to a PICC (1 per 216 PICC days). CRBSI during indwelling PICC was associated with increased risk for sepsis evaluation after PICC removal (P<0.05).
Conclusions:
The incidence of CRBSI in the 48 h following PICC removal was not different than the incidence of CRBSI while a PICC was in-dwelling. There was no evidence from this study to support antibacterial prophylaxis before PICC removal.
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References
Duerkson DR, Papineau N, Siemens J et al. Peripherally inserted central catheters for parenteral nutrition: A comparison with centrally inserted catheters. JPEN Mar-Apr 1999; 23 (2): 85–89.
O’Grady NP, Alexander M, Dellinger EP et al. Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control: MMWR 2002 vol. 51/ No. RR-10.
Craft AP, Finer NN, Barrington KJ . Vancomycin for prophylaxis against sepsis in preterm neonates. Cochrane Library 2004 Issue 2:CD001971.
Isaacs D . A ten year, multicentre study of coagulase negative staphylococcal infections in Australasian neonatal units. Arch Dis Child Fet Neo Ed 2003; 88 (2): F89–F93.
El-Hassan NO, Stephens TP, Gigliotti F et al. Vancomycin usage in central venous catheters in a neonatal intensive care unit. Ped Infect Dis J 2004; 23 (3): 201–206.
Harms K, Herting E, Kron M et al. Randomized controlled trial of amoxicillin prophylaxis for prevention of catheter related infections in newborn infants with central venous silicone elastomer catheters. J. Pediatr. October 1995; 127 (4): 615–619.
Chock VL . Therapeutic techniques: peripherally inserted central catheters in neonates. Neoreviews 2004; 5 (2): e60–e62.
Gonzalez BE, Mercado CK, Johnson L, Brodsky NL, Bhandari V . Early markers of late-onset sepsis in premature neonates: clinical, hematological, and cytokine profile. J Perinat Med. 2003; 31 (1): 60–68.
Mahieu LM, De Muynck OD, Ieven MM, De Dooy JJ, Goossens HJ, Van Reempts PJ . Risk factors for central vascular catheter-associated bloodstream infections among patients in a neonatal intensive care unit. J Hosp Infection 2001; 48: 108–116.
Chathas MK, Paton JB, Fisher DE . Percutaneous central venous catheterization: three years’ experience in a neonatal intensive care unit. Am J Dis Child 1990; 144 (11): 1246–1250.
Pawar M, Mehta Y, Kapoor P et al. Central venous catheter-related blood stream infections: ncidence, risk factors, outcome, and associated pathogens. J Cardiothorac Vasc Anesth. 2004; 18 (3): 304–308.
Acknowledgements
We Thank Terry Leet, PhD. for technical assistance.
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Brooker, R., Keenan, W. Catheter related bloodstream infection following PICC removal in preterm infants. J Perinatol 27, 171–174 (2007). https://doi.org/10.1038/sj.jp.7211655
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DOI: https://doi.org/10.1038/sj.jp.7211655
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