Table 2 Mixed effect model analysis of 24-week repaglinide treatment effect, genotypes effect and their interaction effect.

From: A variation in NOS1AP gene is associated with repaglinide efficacy on insulin resistance in type 2 diabetes of Chinese

Parameters

Repaglinide treatment effect (P value)

Genotypes effect (P value)

Genotypes and treatment interaction effect (P value)

BMI(kg/m2)

0.039

0.064

0.198

Waist-hip ratio

0.907

0.804

0.527

Glycated hemoglobin (%)

<0.001

0.427

0.585

Fasting plasma glucose (mmol/L)

<0.001

0.631

0.573

2-h Plasma glucose (mmol/L)

<0.001

0.494

0.328

HOMA-IR

0.056

0.824

0.013

HOMA-B

<0.001

0.881

0.806

Fasting insulin (pmol/L)

<0.001

0.812

0.103

Acute insulin secretion(pmol/L)

0.270

0.875

0.395

Acute insulin secretion (pmol/L)/Plasma glucose (mmol/L)

0.769

0.032

0.738

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