Table 1 Correlation between the phosphorylation of Akt on Thr308 or Ser473 and the phosphorylation of downstream Akt substrates

From: Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer

 

pPRAS40

pTSC2

pTBC1D4

Akt-pThr308

 R

0.752

0.676

0.465

 p

<0.1 × 10–3

<0.1 × 10–3

8.3 × 10–3

Akt-pSer473

 R

0.352

0.229

0.137

 p

0.052

0.216

0.462

  1. Abbreviations: Ser473=serine 473; Thr308=threonine 308.
  2. The table provides the correlation coefficient (R) and degree of significance (p) obtained for each variable shown using the Spearman's pair-wise correlation test.
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