Table 3 Cox regression model (n=167)

From: IGF-IR: a new prognostic biomarker for human glioblastoma

Model/ P -value

Prognostic factors

Hazard ratio

95% CI

P -value

<10−5

Age

1.02

1.01–1.04

0.003

 

Complete resection

0.67

0.45–0.98

0.039

 

Radiotherapy+temozolomide

0.35

0.17–0.70

0.003

 

IGF-IR positive

1.65

1.10–2.47

0.016

  1. Abbreviations: CI=confidence interval; IGF=insulin-like growth factor. The ‘Model/P-value’ indicates the overall level of significance of the multivariate model. With the exception of ‘Age’, which is a quantitative variable, all of the others are binary. Resection distinguishes between partial and complete, adjuvant treatment between radiotherapy and radiotherapy+temozolomide and IGF-IR between positive (LI1%) and negative (LI<1%). The individual P-values represent the levels of significance of the independent contributions of each factor.