- RESEARCH HIGHLIGHT
Antibodies achieve leptin balancing act
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Nature Reviews Drug Discovery 23, 21 (2024)
doi: https://doi.org/10.1038/d41573-023-00203-9
References
Altarejos, J. Y. et al. Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency. Sci. Transl Med. 15, eadd4897 (2023).
Zhao, S. et al. Hyperleptinemia contributes to antipsychotic drug–associated obesity and metabolic disorders. Sci. Transl Med. 15, eade8460 (2023).