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  • RESEARCH HIGHLIGHT

CRISPR seen in action

Cryo-electron microscopy paints a picture of how the system binds to DNA.
CRISPR systems are used by microbes to fight off attacks, such as from the Pseudomonas aeruginosa bound to an invading phage DNA

CRISPR systems are used by microbes to fight off attacks, such as from the Pseudomonas aeruginosa bound to an invading phage DNA (shown in orange here). V. Falconieri/Subramaniam lab/NCI/NIH

Electron-microscope images reveal how a CRISPR system marks specific DNA sequences for destruction.

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Nature 550, 161 (2017)

doi: https://doi.org/10.1038/d41586-017-04378-1

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