Table 3 Transcripts differentially upregulated and downregulated in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma compared with tumor cells of ALK− anaplastic large cell lymphomaa
Fold change | Gene symbol | Gene name |
|---|---|---|
39.8 | CCL22 | Chemokine (C-C motif) ligand 22 |
26.4 | MMP12 | Matrix metallopeptidase 12 (macrophage elastase) |
11.7 | CHI3L1 | Chitinase 3-like 1 (cartilage glycoprotein-39) |
9.9 | TUBB2B | Tubulin, beta 2B |
9.1 | PTGDS | Prostaglandin D2 synthase 21 kDa (brain) /// prostaglandin D2 synthase 21 kDa (brain) |
8.4 | CD83 | CD83 molecule |
8.2 | — | — |
7.6 | IL1R2 | Interleukin 1 receptor, type II |
5.3 | MCOLN2 | Mucolipin 2 |
4.7 | SLC2A6 | Solute carrier family 2 (facilitated glucose transporter), member 6 |
4.5 | EBI3 | Epstein–Barr virus induced gene 3 |
4.2 | STAT3 | Signal transducer and activator of transcription 3 (acute-phase response factor) |
3.9 | STAT5A | Signal transducer and activator of transcription 5A |
3.8 | SOCS3 | Suppressor of cytokine signaling 3 |
3.7 | APBB1IP | Amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
3.6 | RAB13 | RAB13, member RAS oncogene family |
3.5 | BASP1 | Brain abundant, membrane attached signal protein 1 |
3.4 | IER3 | Immediate early response 3 |
−1.9 | HIST1H4C | Histone 1, H4c |
−2.0 | — | — |
−2.2 | — | CDNA FLJ37566 fis, clone BRCOC2002085 |
−2.2 | EEF1D | Eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
−2.3 | RPS27 | Ribosomal protein S27 (metallopanstimulin 1) |
−2.3 | RPS10 | Ribosomal protein S10 |
−2.5 | RNPS1 | RNA binding protein S1, serine-rich domain |
−2.7 | NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14 kDa |
−2.9 | SAC3D1 | SAC3 domain containing 1 |
−3.2 | ATP6V0E | ATPase, H+ transporting, lysosomal 9 kDa, V0 subunit e |
−3.4 | LOC653784 | Similar to hypothetical protein FLJ14346 |
−3.5 | NDUFA4 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9 kDa |
−3.5 | BTBD6 | BTB (POZ) domain containing 6 |
−3.9 | — | Transcribed locus, strongly similar to XP_511906.1 PREDICTED: similar to KIAA0612 protein [Pan troglodytes] |
−5.0 | CAPN2 | Calpain 2, (m/II) large subunit |
