Figure 3
From: ‘Non-classical’ HER2 FISH results in breast cancer: a multi-institutional study
Breakdown of ‘Non-classical’ amplified results. Amplified cases with non-classical results were grouped into the following categories defined as follows: (1) ‘monosomy’ (ratio ≥2.0, mean HER2/cell<4.0); (2) ‘co-amplified/polysomy’ (ratio<2.0, mean HER2/cell ≥6.0); (3) ‘low amplified’ (ratio ≥2.0, mean HER2/cell 4.0–5.9). Cases with clusters of amplified cells representing at least 10% of the population were defined as heterogeneous.
