Table 3 Clusters showing similar and different grey-matter changes in MDD and BD

From: Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis

Peak MNI coordinate

Z

P

Voxels

Brodmann areas

Regions

MDD<BD

 34, 30, 40

−2.46

<0.001

102

9, 46

Right middle frontal gyrus

 −26, −38, −2

−2.47

<0.001

74

37

Left hippocampus, parahippocampal gyrus

 42, −26, −22

−2.33

<0.001

72

20

Right inferior temporal gyrus, fusiform gyrus

 −40, −52, 44

−2.25

<0.001

31

40

Left inferior parietal lobule

 4, −42, −22

−2.10

<0.001

14

—

Right cerebellar vermis

Reductions in both MDD and BD

 52, −4, 2

4.97

<0.001

753

48

Right superior temporal gyrus, insula

 −42, 0, −2

4.69

<0.001

377

38, 48

Left insula, superior temporal gyrus

 −4, 54, 18

4.28

0.001

115

10, 32

Left superior medial frontal gyrus, anterior cingulate cortex

 4, 48, 22

4.20

0.001

50

32

Right anterior cingulate cortex

  1. Abbreviations: BD, bipolar disorder; MDD, major depression disorder.
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