Injured blood vessels are repaired by vascular smooth-muscle cells. It emerges that the protein Fat1 regulates the proliferation of these cells by inhibiting the function of mitochondria. See Letter p.575
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Notes
References
Cao, L. L. et al. Nature 539, 575–578 (2016).
Sadeqzadeh, E., de Bock, C. E. & Thorne, R. F. Med. Res. Rev. 34, 190–221 (2014).
Hou, R., Liu, L., Anees, S., Hiroyasu, S. & Sibinga, N. E. S. J. Cell Biol. 173, 417–429 (2006).
Chiong, M. et al. Front. Cell Dev. Biol. 2, 72 (2014).
Mahoney, P. A. et al. Cell 67, 853–868 (1991).
Morris, L. G. T. et al. Nature Genet. 45, 253–261 (2013).
de Bock, C. E. et al. Leukemia 26, 918–926 (2012).
Kranz, D. & Boutros, M. EMBO J. 33, 181–197 (2014).
Madan, E. et al. Int. J. Cancer 139, 2570–2582 (2016).
Sing, A. et al. Cell 158, 1293–1308 (2014).
Magg, T., Schreiner, D., Solis, G. P., Bade, E. G. & Hofer, H. W. Exp. Cell Res. 307, 100–108 (2005).
Bray, S. J. Nature Rev. Mol. Cell Biol. 17, 722–735 (2016).
Gao, Y., Chen, T. & Raj, J. U. Am. J. Respir. Cell Mol. Biol. 54, 451–460 (2016).
Author information
Authors and Affiliations
Corresponding author
Related links
Rights and permissions
About this article
Cite this article
de Bock, C., Thorne, R. A mitochondrial brake on vascular repair. Nature 539, 503–504 (2016). https://doi.org/10.1038/nature20476
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature20476