Nancy J Kelley is the founder and chief executive of Nancy J Kelley + Associates, a consultancy creating and developing projects and institutions for science and medicine. She also is the founding executive director of the New York Genome Center. Her conversation with Nature Biotechnology touches on establishing the East River Science Park, excelling at Yale as a young mother of three and why one must take risks in life. http://www.nature.com/nbt/podcast/archive.html