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Myriad's impact on gene patents

Nature Biotechnology volume 34, pages 1119–1123 (2016)Cite this article

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Three years later, the landmark Myriad decision on gene patents has led to some striking and unforeseen implications.

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Figure 1
Figure 2: Granted patents with gene-related claims containing sequence IDs, including the gene-related search terms identified in search S1 (general) and S2 (isolated) from Table 1, as well as the keyword 'isolated' within three words of 'DNA.'
Figure 3: Gene-related patents (a) filed in the last 20 years containing the S3 search terms in Table 1 and (b) including the keyword “isolated” within 3 words of DNA in the claims.

References

  1. Association for Molecular Pathology v. Myriad Genetics, Inc., 133 S. Ct. 2107 (2013).

  2. Burk, D.L. J. Law Biosci. 2, 606–626 (2015).

    PubMed  PubMed Central  Google Scholar 

  3. In re BRCA1- & BRCA2- Based Hereditary Cancer Test Patent Litig v. Ambry Genetics Corp., 774 F.3d 755 (Fed. Cir. 2014).

  4. Sherkow, J.S. & Greely, H.T. Annu. Rev. Genet. 49, 161–182 (2015).

    Article  CAS  Google Scholar 

  5. Guerrini, C.J., Majumder, M.A. & McGuire, A.L. Nat. Biotechnol. 34, 145–147 (2016).

    Article  CAS  Google Scholar 

  6. Graff, G.D. et al. Nat. Biotechnol. 31, 404–410 (2013).

    Article  CAS  Google Scholar 

  7. Gordon, J. Cold Spring Harb. Perspect. Med. 5, http://dx.doi.org/10.1101/cshperspect.a020917 (2014).

  8. Cook-Deegan, R. & Niehaus, A. Curr. Genet. Med. Rep. 2, 223–241 (2014).

    Article  Google Scholar 

  9. Woessner, W.D. & Chadwick, R.A. Pharm. Pat. Anal. 2, 165–167 (2013).

    Article  CAS  Google Scholar 

  10. Ratner, M. Nat. Biotechnol. 31, 663–665 (2013).

    Article  CAS  Google Scholar 

  11. Gold, R.E., Cook-Deegan, R. & Bubela, T. Sci. Transl. Med. 5, 192ed9 (2013).

    Article  Google Scholar 

  12. Offit, K. et al. J. Clin. Oncol. 31, 2743–2748 (2013).

    Article  Google Scholar 

  13. Bubela, T. et al. Nat. Biotechnol. 31, 202–206 (2013).

    Article  CAS  Google Scholar 

  14. Cook-Deegan, R. & Heaney, C. Annu. Rev. Genomics Hum. Genet. 11, 383–425 (2010).

    Article  CAS  Google Scholar 

  15. Hopkins, M.M., Mahdi, S., Patel, P. & Thomas, S.M. Nat. Biotechnol. 25, 185–187 (2007).

    Article  CAS  Google Scholar 

  16. 35 USC § 101.

  17. 35 USC § 102.

  18. 35 USC § 103.

  19. Mayo Collaborative Services v. Prometheus Laboratories, Inc., 132 S. Ct. 1289 (2012).

  20. Alice Corporation v. CLS Bank International, 132 S. Ct. 2347 (2014).

  21. Arora, A., Fosfuri, A. & Gambardella, A. Markets for Technology (MIT Press, 2001).

    Book  Google Scholar 

  22. Sichelman, T. & Graham, S.J. Mich. Telecomm. & Tech. L. Rev. 17, 111–180 (2010).

    Google Scholar 

  23. http://www.scotusblog.com/case-files/cases/association-for-molecular-pathology-v-myriad-genetics-inc/

  24. Royzman, I. Nat. Biotechnol. 33, 925–926 (2015).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Mateo Aboy, Kathleen Liddell, Johnathon Liddicoat and Cristina Crespo are in the Centre of Law, Medicine, and Life Sciences (LML), Faculty of Law, University of Cambridge, Cambridge, UK.,

    Mateo Aboy, Kathleen Liddell, Johnathon Liddicoat & Cristina Crespo

  2. Mateo Aboy is also in the College of Engineering, Technology and Management, Oregon Institute of Technology, Klamath Falls, Oregon, USA.,

    Mateo Aboy

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  1. Mateo Aboy
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  2. Kathleen Liddell
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Correspondence to Mateo Aboy.

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Supplementary information

Supplementary Figures

Supplementary Figures 1–4 (PDF 344 kb)

Supplementary Table 1

Key Empirical Research on DNA-related patent protection (PDF 146 kb)

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Aboy, M., Liddell, K., Liddicoat, J. et al. Myriad's impact on gene patents. Nat Biotechnol 34, 1119–1123 (2016). https://doi.org/10.1038/nbt.3719

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