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A helicase that gets Oskar's message across

Nature Cell Biology volume 6, pages 285–287 (2004)Cite this article

Messenger RNA localization is a common way of targeting proteins to their site of function. This process is dependent on RNA signals that are interpreted by trans-acting factors. A putative RNA helicase and translational initiation factor is now shown to form a conserved complex, important for localization of oskar mRNA in Drosophila melanogaster and RNA surveillance in human cells.

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Figure 1: Ribonucleoprotein sorting during fly oogenesis.
Figure 2: eIF4AIII, Btz and Mago-Y14 may be recruited at distinct stages.

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  1. the Wellcome Trust Centre for Cell Biology, University of Edinburgh, Mayfield Road, Edinburgh, EH9 3JR, UK

    Ilan Davis

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  1. Ilan Davis
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Davis, I. A helicase that gets Oskar's message across. Nat Cell Biol 6, 285–287 (2004). https://doi.org/10.1038/ncb0404-285

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