Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

TACCing down the spindle poles

Nature Cell Biology volume 3, pages E159–E160 (2001)Cite this article

Centrosomes define the poles of mitotic spindles, but spindles that lack centrosomes mediate meiotic chromosome segregation in females. Recent studies provide new insight into anastral-spindle assembly, and indicate that a conserved protein complex may be critical to the stability of both the astral- and anastral-spindle pole.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Assembly of an anastral-spindle pole.

References

  1. Wilson, E. B. The Cell in Development and Heredity (MacMillan, New York, 1925).

    Google Scholar 

  2. Merdes, A. & Cleveland, D. W. J. Cell Biol. 138, 953–956 (1997).

    Article  CAS  Google Scholar 

  3. Cullen, C. F. & Ohkura, H. Nature Cell Biol. 3, 637–642 (2001).

    Article  CAS  Google Scholar 

  4. Lee, M. J., Gergely F., Jeffers, K., Peak-Chew, S. Y. & Raff, J. W. Nature Cell Biol. 3, 643–649 (2001).

    Article  CAS  Google Scholar 

  5. Hawley, R. S., McKim, K. S. & Arbel, T. Annu. Rev. Genet. 27, 281–317 (1993).

    Article  CAS  Google Scholar 

  6. Walker, R. A., Salmon, E. D. & Endow, S. A. Nature 347, 780–782 (1990).

    Article  CAS  Google Scholar 

  7. Kimble, M. & Church, K. J. Cell Sci. 62, 301–318 (1983).

    CAS  PubMed  Google Scholar 

  8. Matthies, H. J., McDonald, H. B., Goldstein, L. S. & Theurkauf, W. E. J. Cell Biol. 134, 455–464 (1996).

    Article  CAS  Google Scholar 

  9. Charrasse, S. et al. J. Cell Sci. 111, 1371–1383 (1998).

    CAS  PubMed  Google Scholar 

  10. Cullen, C. F., Deak, P., Glover, D. M. & Ohkura, H. J. Cell Biol. 146, 1005–1018 (1999).

    Article  CAS  Google Scholar 

  11. Tournebize, R. et al. Nature Cell Biol. 2, 13–19 (2000).

    Article  CAS  Google Scholar 

  12. Gergely, F. et al. Proc. Natl Acad. Sci. USA 97, 14352–14357 (2000).

    Article  CAS  Google Scholar 

  13. Theurkauf, W. E. & Hawley, R. S. J. Cell Biol. 116, 1167–1180 (1992).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. the Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, 01605, Massachusetts, USA

    William E. Theurkauf

Authors
  1. William E. Theurkauf
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Theurkauf, W. TACCing down the spindle poles. Nat Cell Biol 3, E159–E160 (2001). https://doi.org/10.1038/35083110

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/35083110

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing