An acknowledged key to the success of Mycobacterium tuberculosis as a pathogen is its ability to prevent the fusion of a phagosome containing the internalized bacterium with the host cell's lysosomal system. Recent work examines the modulation of phagosome maturation by addition of exogenous fatty acids and discusses the implications that this could have for anti-tuberculosis therapy or prophylaxis.
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Russell, D. Phagosomes, fatty acids and tuberculosis. Nat Cell Biol 5, 776–778 (2003). https://doi.org/10.1038/ncb0903-776
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DOI: https://doi.org/10.1038/ncb0903-776
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