A small molecule's biological activity in a cell depends on the actions of many gene products. Correlations between basal gene expression and compound sensitivity across hundreds of human cell lines reveal a broad view of cellular mechanisms of action.
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Palmer, A. The many genes of drug mechanism. Nat Chem Biol 12, 57–58 (2016). https://doi.org/10.1038/nchembio.2010
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DOI: https://doi.org/10.1038/nchembio.2010
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