Synthetic organic chemistry of complex natural products and their substructures provides challenges for the chemist and invaluable tools for the biologist. The production of a 'GPI chip', a device for simultaneously measuring and characterizing antibody responses to GPI structures, is applied to dissect malaria-induced antibody responses.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Kamena, F. et al. Nat. Chem. Biol. 4, 238–240 (2008).
Fukui, S., Feizi, T., Galustian, C., Lawson, A.M. & Chai, W. Nat. Biotechnol. 20, 1011–1017 (2002).
Stevens, J., Blixt, O., Paulson, J.C. & Wilson, I.A. Nat. Rev. Microbiol. 4, 857–864 (2006).
Nebl, T., De Veer, M.J. & Schofield, L. Parasitology 130 (suppl.), 45–62 (2005).
Gowda, D.C. Trends Parasitol. 23, 596–604 (2007).
Schofield, L., Hewitt, M.C., Evans, K., Siomos, M.A. & Seeberger, P.H. Nature 418, 785–789 (2002).
Naik, R.S., Krishnegowda, G., Ockenhouse, C.F. & Gowda, D.C. Infect. Immun. 74, 1412–1415 (2006).
Fankhauser, C. et al. J. Biol. Chem. 268, 26365–26374 (1993).
Fontaine, T. et al. Glycobiology 13, 169–177 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ferguson, M. GPIs on a chip. Nat Chem Biol 4, 223–224 (2008). https://doi.org/10.1038/nchembio0408-223
Issue Date:
DOI: https://doi.org/10.1038/nchembio0408-223