A phosphorothioate modification of DNA has been identified in bacteria. This first observed alteration of the DNA phosphate backbone opens many questions about the mechanism of sulfur incorporation and the function of this modification.
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Eckstein, F. Phosphorothioation of DNA in bacteria. Nat Chem Biol 3, 689–690 (2007). https://doi.org/10.1038/nchembio1107-689
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DOI: https://doi.org/10.1038/nchembio1107-689
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