Figure 3: 2D flow nanometry applied to gold NPs.
Comparison of size distributions of gold NP batches determined using EM (a,b) and 2D flow nanometry (c,d). The distributions are essentially identical and are only shifted by 5 nm, which is attributed to a 5 nm PEG corona formed on the surface of the gold nanoparticles that is not resolved in EM34. Note that the widths of the distributions are indicative for the polydispersity of the gold NP samples, but not the measurement accuracy of the approaches, which is on the nm-scale.
