Figure 4: Trait variation determination in non-T-cell subsets.
From: Innate and adaptive immune traits are differentially affected by genetic and environmental factors
(a) B-cell traits were arranged according to lineage (B1 or conventional B2) and among B2, by surface isotype expression (here, cells that co-express IgM and IgD are labelled as IgD; those that express only IgM are labelled as IgM). (b) DC traits are arranged by subset phenotype. ‘pDC’, plasmacytoid DC (CD11c−CD123+). ‘xDC’, DC co-expressing CD11c and CD123. All others are myeloid DC (mDC, CD11c+CD123−), including mDC-1 (CD1c−CD16−), antigen-presenting cells for CD4 T cells (‘CD4 APC’, CD1c+), antigen-presenting cells for CD8 T cells (‘CD8 APC’, CD141+) and inflammatory mDC (‘imDC’, CD1c−CD16+). (c) Monocyte traits are divided by the coordinate expression of CD16 and CD274.
