Table 2 Association between neuropsychiatric CNVs and number of children.
From: Reproductive fitness and genetic risk of psychiatric disorders in the general population
CNV | Odds ratio (autism/schizophrenia) | Carriers (male/female) | Non-carriers (male/female) | Beta (male/female) | P value (male/female) |
|---|---|---|---|---|---|
All CNVs | 201/268 | 42,826/49,161 | −0.405/−0.184 | 0.00028/0.050 | |
Autism CNVs | 37/60 | 42,990/49,369 | −1.263/−0.481 | 9.4E−07/0.014 | |
Schizophrenia CNVs | 189/256 | 42,838/49,173 | −0.266/−0.115 | 0.021/0.23 | |
16p11.2 del | inf/NA | 12/12 | 43,015/49,417 | −2.534/−1.59 | 1.8E−08/0.00025 |
1q21.1 del | NA/8.35 | 11/15 | 43,016/49,414 | −0.741/−0.98 | 0.12/0.012 |
22q11.21 del | NA/inf | 3 | 92,453 | −1.421 | 0.11 |
16p11.2 dup | 4.1/11.52 | 39 | 92,417 | −0.326 | 0.19 |
15q11.2—13.1 dup | inf/13.20 | 4 | 92,452 | −0.926 | 0.23 |
7q11.23 (WBS) dup | NA/11.35 | 3 | 92,453 | −1.150 | 0.23 |
15q13.3 all del | inf/7.52 | 19 | 92,437 | −0.343 | 0.34 |
16p13.1 dup | NA/2.30 | 103 | 92,353 | −0.128 | 0.41 |
2p16.1 (NRXN1) del | 5.6/9.01 | 11 | 92,445 | −0.353 | 0.45 |
15q11.2 all del | NA/2.15 | 192 | 92,264 | −0.058 | 0.61 |
1q21.1 dup | NA/3.45 | 38 | 92,418 | 0.049 | 0.85 |
