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Should aspirin be used as a preventive therapy for thrombosis in patients with antiphospholipid antibodies?

Nature Clinical Practice Rheumatology volume 4, pages 14–15 (2008)Cite this article

boxed-textErkan D et al. (2007) Aspirin for primary thrombosis prevention in the antiphospholipid syndrome. A randomized, double-blind, placebo-controlled trial in asymptomatic antiphospholipid antibody-positive individuals. Arthritis Rheum 56: 2382–2391

In asymptomatic patients with persistently positive antiphospholipid antibody, aspirin is not effective for the primary prevention of thrombosis

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References

  1. Wilson WA et al. (1999) International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop. Arthritis Rheum 42: 1309–1311

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Acknowledgements

The synopsis was written by Jasmine Farsarakis, Associate Editor, Nature Clinical Practice.

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Author notes

  1. Division of Rheumatology, University of Oklahoma, Health Sciences Center, Bielstein 3B3303, OU Children's Physicians Building, 940 NE 13th Street, Oklahoma City, OK 73104, USA kathleen-oneil@ouhsc.edu

Authors and Affiliations

  1. KM O'Neil is Associate Professor of Pediatrics in the Division of Rheumatology at the University of Oklahoma Health Sciences Center, Oklahoma, OK, USA.,

    Kathleen M O'Neil

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The author declares no competing financial interests.

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O'Neil, K. Should aspirin be used as a preventive therapy for thrombosis in patients with antiphospholipid antibodies?. Nat Rev Rheumatol 4, 14–15 (2008). https://doi.org/10.1038/ncprheum0682

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