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A common mechanism for microcephaly

Nature Genetics volume 42, pages 923–924 (2010)Cite this article

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New studies employing high-throughput parallel sequencing have revealed WDR62 mutations in individuals with microcephaly associated with a broad range of malformations of cortical development. These findings establish that WDR62 acts as a molecular link between proliferation and migration in neurogenesis.

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Figure 1: WDR62 function during cortical development.

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  1. Bernd Wollnik is at the Center for Molecular Medicine Cologne (CMMC), Institute of Human Genetics, and Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.,

    Bernd Wollnik

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  1. Bernd Wollnik
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Correspondence to Bernd Wollnik.

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Wollnik, B. A common mechanism for microcephaly. Nat Genet 42, 923–924 (2010). https://doi.org/10.1038/ng1110-923

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