TREC assays are used to detect recent thymic emigrants and quantitate thymic output. However, the longevity of naive T cells combined with T cell division suggest TREC data should be interpreted with caution.
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We would like to thank H. Schuitemaker for critical reading of the manuscript.
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Hazenberg, M., Borghans, J., de Boer, R. et al. Thymic output: a bad TREC record. Nat Immunol 4, 97–99 (2003). https://doi.org/10.1038/ni0203-97
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DOI: https://doi.org/10.1038/ni0203-97
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