Maintenance of a memory cell population is thought to be independent of antigen. However, it has now been shown that unless memory cells get some signals via MHC, they become functionally defective.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Kassiotis, G. et al. Nature Immunol. 3, 244–250 (2002).
Lau, L. L., Jamieson, B. D., Somasundaram, T. & Ahmed, R. Nature 369, 648–652 (1994).
Hou, S. et al. Nature 369, 652–654 (1994).
Tanchot, C. et al. Science 276, 2057–2062 (1997).
Markiewicz, M. A. et al. Proc. Natl Acad. Sci. USA 95, 3065–3070 (1998).
Polik, B., Kunkel, D., Scheffold, A. & Rajewsky, K. Proc. Natl Acad. Sci. USA 98, 8744–8749 (2001).
Murali-Krishna, K. et al. Science 286, 1377–1381 (1999).
Swain, S. L., Hu, H. & Huston, G. Science 286, 1381–1383 (1999).
Kundig, T. M. et al. Immunol. Rev. 150, 63–90 (1996).
Off, G. S. et al. Science 279, 2103–2106 (1998).
Veiga-Fernandes, H. et al. Nature Immunol. 1, 47–53 (2000).
Panus, J. F., McHeyzer-Williams, L. J. & McHeyzer-Williams, M. G. J. Exp. Med. 192, 1301–1316 (2000).
Rocha, B., Grandien, A. & Freitas, A. A. . J. Exp. Med. 181, 993–1003 (1995).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rocha, B. Requirements for memory maintenance. Nat Immunol 3, 209–210 (2002). https://doi.org/10.1038/ni0302-209
Issue Date:
DOI: https://doi.org/10.1038/ni0302-209