The function of the mammalian TIR domain adaptor protein SARM is unclear. In Caenorhabditis elegans, however, the homolog of SARM controls the induction of peptides involved in innate immunity.
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Hodgkin, J. Dissecting worm immunity. Nat Immunol 5, 471–472 (2004). https://doi.org/10.1038/ni0504-471
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DOI: https://doi.org/10.1038/ni0504-471