Lymphocyte development must be tightly regulated in utero to prevent rejection. New work shows that the zinc finger protein Zfp608 negatively regulates the expression of recombination-activating genes 1 and 2 and may suppress fetal T cell development.
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Carpenter, A., Bassing, C. Fetal thymocyte development: putting a zinc finger on it?. Nat Immunol 7, 1285–1286 (2006). https://doi.org/10.1038/ni1206-1285
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DOI: https://doi.org/10.1038/ni1206-1285