The retinoblastoma gene (RB) was the first tumor suppressor gene cloned. But, until recently, little clinical progress had been made to target human tumors deficient in RB function. A new approach emerges from studying retinoblastoma tumors.
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Katie Ris
References
Weinberg, R.A. Cell 81, 323–330 (1995).
Abramson, D.H. & Schefler, A.C. Retina 24, 828–848 (2004).
Laurie, N.A. et al. Nature 444, 61–66 (2006).
Sherr, C.J. & McCormick, F. Cancer Cell 2, 103–112 (2002).
Ringshausen, I., O'Shea, C.C., Finch, A.J., Brown Swigart, L. & Evan, G.I. Cancer Cell 10, 501–514 (2006).
Johnson, L. et al. Cancer Cell 1, 325–337 (2002).
Nikitin, A.Y., Juarez-Perez, M.I., Li, S., Huang, L. & Lee, W.H. Proc. Natl. Acad. Sci. USA 96, 3916–3921 (1999).
Ying, H. & Xiao, Z.X. Cell Cycle 5, 506–508 (2006).
Classon, M. & Harlow, E. Nat. Rev. Cancer 2, 910–917 (2002).
Tedesco, D., Lukas, J. & Reed, S.I. Genes Dev. 16, 2946–2957 (2002).
Adams, J. Cancer Cell 5, 417–421 (2004).
Meijer, L. & Raymond, E. Acc. Chem. Res. 36, 417–425 (2003).
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Sage, J. Hope in sight for retinoblastoma. Nat Med 13, 30–31 (2007). https://doi.org/10.1038/nm0107-30
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DOI: https://doi.org/10.1038/nm0107-30
