Pollutant research is moving indoors as scientists uncover new links between indoor exposure and disease. However, measuring the levels of exposure is a difficult task.
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References
Neas, L.M., Dockery, D.W., Ware, J.H., Spengler, J.D., Speizer, F.E. & Ferris, B.G. Association of indoor nitrogen dioxide with respiratory symptoms and pulmonary function in children. Am. J. Epidemiol. 134, 204–219 (1991).
Roger, L.J. et al. Pulmonary effects in asthmatics exposed to 0.3 ppm NO2 during repeated exercise. Toxicology 5, 70 (1985).
Bauer, M.A., Utell, M.J., Morrow, P.E., Speers, D.M. & Gibb, F.R. Inhalation of 0.3 ppm nitrogen dioxide potentiates exercise-induced bronchospasm in asthmatics. Am. Rev. respir. Dis. 134, 1203–1208 (1986).
Houthuijs, D., Remijn, B., Brunekreef, B. & DeKoning, R. Exposure to nitrogen dioxide and tobacco smoke and respiratory health of children. Indoor Air 1, 463–467 (1987).
Dijkstra, L., Houthuijs, D., Brunekreef, B., Akkerman, I. & Boleij, J.S. Respiratory health effects of the indoor environment in a population of Dutch children. Am. Rev. respir. Dis. 142, 1172–1178 (1990).
Samet, J.M. et. al. Nitrogen dioxide and respiratory illness in infants. Am. Rev. respir. Dis. 148, 1258–1265 (1993).
Samet, J.M., Marbury, M.C. & Spengler, J.D. Health effects and sources of indoor air pollution. Part 1. Am. Rev. respir. Dis. 136, 1486–1508 (1987).
Devalia, J.L., Rusznak, C., Herdman, M.J., Trigg, C.J., Tarraf, H. & Davies, R.J. Effects of nitrogen dioxide and sulphur dioxide on airway response of mild asthmatic patients to allergen inhalation. Lancet 344, 1668–1671 (1994).
Tunnicliffe, W.S., Burge, P.S. & Ayres, J.G. Effect of domestic concentrations of nitrogen dioxide on airway responses to inhaled allergen in asthmatic patients. Lancet 344, 1733–1736 (1994).
Abramson, M. & Voigt, T. Ambient air pollution and respiratory disease. Med. J. Aust. 154, 543–553 (1991).
Morrow, P.E. & Utell, M.J. Responses of susceptible subpopulations to nitrogen dioxide. Research Report Number 23. (Health Effects Institute, Cambridge, Massachusetts, 1989).
Frampton, M.W., Morrow, P.E., Cox, C., Gibb, F.R., Speers, D.M. & Utell, M.J. Effects of nitrogen dioxide exposure on pulmonary function and airways reactivity in normal humans. Am. Rev. respir. Dis. 143, 522–527 (1991).
Frampton, M.W., Smeglin, A.M., Roberts, N.J., Finkelstein, J.N., Morrow, P.E. & Utell, M.J. Nitrogen dioxide exposure in vivo and human alveolar macrophage inactivation of influenza virus in vitro. Environ. Res. 48, 179–192 (1989).
Frampton, M.W. et al. Environmental factors and atmospheric pollutants. Semin. Res. Infect. 6, 185–193 (1991).
Graham, J.A., Gardner, D.E., Blommer, E.J., House, D.E., Menache, M.G. & Miller, F.J. Influence of exposure patterns of nitrogen dioxide and modifications by ozone on susceptibility to bacterial infectious disease in mice. J. Tox. envir. Hlth 21, 113–125 (1987).
Gardner, D.E., Miller, F.J., Blommer, E.J. & Coffin, D.L. Influence of exposure mode on the toxicity of NO2 . Envir. Hlth Perspect. 30, 23–29 (1979).
Miller, F.J. et al. Evaluating the toxicity of urban patterns of oxidant gases. II. Effects in mice from chronic exposure to nitrogen dioxide. J. Tox. envir. Hlth 21, 99–112 (1987).
Members of the European Community's Concertation Committee. Effects of indoor air pollution on health. in Environmental Carcinogens: Methods of Analysis and Exposure Measurement (eds Seifert, B., van de Wiel, H.J., Dodet, B. & O'Neill, I.K.) Vol. 12. (International Agency for Research on Cancer, Lyon, 1993).
Pilotto, L.S. Indoor nitrogen dioxide exposure and respiratory illness in children. (Ph.D. thesis, National Centre for Epidemiology and Population Health, The Australian National University 1994).
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Pilotto, L., Douglas, R. Measuring NO2 exposure in respiratory disease. Nat Med 1, 517–518 (1995). https://doi.org/10.1038/nm0695-517
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DOI: https://doi.org/10.1038/nm0695-517