A new mass spectrometry (MS) approach has been developed, allowing combinatorial analysis of histone H3.2 post-translational modifications that may provide the key to unlocking the histone code.
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References
Jenuwein, T. & Allis, C.D. Science 293, 1074–1080 (2001).
Garcia, B.A., Pesavento, J.J., Mizzen, C.A. & Kelleher, N.L. Nat. Methods 4, 487–489 (2007).
Zubarev, R.A., Kelleher, N.L. & McLafferty, F.W. J. Am. Chem. Soc. 120, 3265–3266 (1998).
Syka, J.E., Coon, J.J., Schroeder, M.J., Shabanowitz, J. & Hunt, D.F. Proc. Natl. Acad. Sci. USA 101, 9528–9533 (2004).
Pesavento, J.J., Kim, Y.B., Taylor, G.K. & Kelleher, N.L. J. Am. Chem. Soc. 126, 3386–3387 (2004).
Medzihradszky, K.F. et al. Mol. Cell. Proteomics 3, 872–886 (2004).
Boyne, M.T., II, Pesavento, J.J., Mizzen, C.A. & Kelleher, N.L. J. Proteome Res. 5, 248–253 (2006).
Siuti, N., Roth, M.J., Mizzen, C.A., Kelleher, N.L. & Pesavento, J.J. J. Proteome Res. 5, 233–239 (2006).
Taverna, S.D. et al. Proc. Natl. Acad. Sci. USA 104, 2086–2091 (2007).
Proudfoot, N.J., Furger, A. & Dye, M.J. Cell 108, 501–512 (2002).
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Gilmore, J., Washburn, M. Deciphering the combinatorial histone code. Nat Methods 4, 480–481 (2007). https://doi.org/10.1038/nmeth0607-480
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DOI: https://doi.org/10.1038/nmeth0607-480
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