Amyotrophic lateral sclerosis is an incurable paralyzing disorder caused by the death of motor neurons in the spinal cord and brainstem. Patients typically die within three to five years. In this issue, Storkebaum and colleagues offer new evidence for VEGF action in motor neuron survival and new hope for direct delivery of VEGF into the nervous system as a therapy for ALS.
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Velde, C., Cleveland, D. VEGF: multitasking in ALS. Nat Neurosci 8, 5–7 (2005). https://doi.org/10.1038/nn0105-5
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DOI: https://doi.org/10.1038/nn0105-5
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