Abstract
Semaphorins A and E are known to potently repel sympathetic axons. New work indicates that they can also antagonize the repellent action of semaphorin D at sensory axons.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Secreted semaphorin 5A suppressed pancreatic tumour burden but increased metastasis and endothelial cell proliferation
British Journal of Cancer Open Access 10 July 2012
-
Effect of cancer-associated mutations in the PlexinB1 gene
Molecular Cancer Open Access 09 March 2012
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Tessier-Lavigne, M. & Goodman, C. S. Science 274, 1123–1133 (1996).
Takahashi, T., Nakamura, F., Jin, Z., Kalb, R. G. & Strittmatter, S. M. Nature Neurosci. 1, 487– 493 (1998).
Kolodkin, A. L. et al. Neuron 9, 831–845 (1992).
Luo, Y.-L., Raible, D. & Raper, J. A. Cell 75, 217– 227 (1993).
Kolodkin, A. L., Matthes, D. J. & Goodman, C. S. Cell 75, 1389– 1399 (1993).
Mark, M. D., Lohrum, M. & Puschel, A. W. Cell Tissue Res. 290, 299– 306 (1997).
Messersmith, E. K. et al. Neuron 14, 949–959 (1995).
Taniguchi, M. et al. Neuron 19, 519–530 (1997).
Takagi, S. et al. Neuron 7, 295–307 (1991).
He, Z. & Tessier-Lavigne, M. Cell 90, 739–751 (1997).
Kolodkin, A. L. et al. Cell 90, 753–762 (1997).
Kitsukawa, T. et al. Neuron 19, 995–1005 (1997).
Chen, H., Chedotal, A., He, Z., Goodman, C. S. & Tessier-Lavigne, M. Neuron 19, 547– 559 (1997).
Feiner, L., Koppel, A. M., Kobayashi, H. & Raper, J. A. Neuron 19, 539–545 (1997).
Soker, S., Takashima, S., Miao, H. Q., Neufeld, G. & Klagsbrun, M. Cell 92, 735–745 (1998).
Comeau, M. R. et al. Immunity 8, 473–482 (1998).
Ohta, K. et al. Neuron 14, 1189–1199 (1995).
Maestrini, E. Proc. Natl. Acad. Sci. USA 93, 674– 678 (1996).
Xu, X. et al. J. Biol. Chem. 273, 22428– 22434 (1998).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Chen, H., He, Z. & Tessier-Lavigne, M. Axon guidance mechanisms: semaphorins as simultaneous repellents and anti-repellents. Nat Neurosci 1, 436–439 (1998). https://doi.org/10.1038/2154
Issue Date:
DOI: https://doi.org/10.1038/2154
This article is cited by
-
The peritoneum—an important factor for pathogenesis and pain generation in endometriosis
Journal of Molecular Medicine (2014)
-
Immunological functions of the neuropilins and plexins as receptors for semaphorins
Nature Reviews Immunology (2013)
-
Effect of cancer-associated mutations in the PlexinB1 gene
Molecular Cancer (2012)
-
Analysis of axonal growth and cell migration in 3D hydrogel cultures of embryonic mouse CNS tissue
Nature Protocols (2012)
-
Secreted semaphorin 5A suppressed pancreatic tumour burden but increased metastasis and endothelial cell proliferation
British Journal of Cancer (2012)