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Nanomedicine

AFM tackles osteoarthritis

Current diagnostic tools detect cartilage degeneration only at advanced stages, but the atomic force microscope can now detect structural changes earlier, paving the way for treatment of joint diseases.

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Figure 1: The intermediate and late stages of osteoarthritis show up as narrowing of the joint space: the arrows in the left X-ray image point to a joint space in the knee of a healthy individual, whereas the arrows in the right image point to the reduced joint space in the knee of someone with intermediate-stage osteoarthritis.

DR E. WELKERLING

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Aigner, T., Schmitz, N. & Haag, J. AFM tackles osteoarthritis. Nature Nanotech 4, 144–145 (2009). https://doi.org/10.1038/nnano.2009.29

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