Table 1 Relationships between mGluR1/5 and trafficking proteins in the CA1 region
From: Molecular evidence of synaptic pathology in the CA1 region in schizophrenia
Controls | Schizophrenia | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total | Monomer | Dimer | Total | Monomer | Dimer | |||||||
mGluR1 | ||||||||||||
Homer1a | r =−0.654** | P =0.004 | r =−0.612** | P =0.005 | r=−0.429 | P=0.059 | r=−0.239 | P=0.390 | r=−0.071 | P=0.795 | r=−0.287 | P=0.264 |
Homer1b/c | r=0.331 | P=0.195 | r =0.549* | P =0.015 | r=0.361 | P=0.118 | r=0.218 | P=0.455 | r=0.064 | P=0.820 | r=0.153 | P=0.572 |
PSD95 | r =0.612* | P =0.012 | r=0.465 | P=0.052 | r =0.530* | P =0.020 | r=0.409 | P=0.116 | r=0.365 | P=0.149 | r=0.337 | P=0.171 |
Tamalin | r=0.463 | P=0.061 | r =0.500* | P =0.029 | r=0.376 | P=0.102 | r =0.526* | P =0.036 | r=0.395 | P=0.117 | r=0.348 | P=0.157 |
mGluR5 | ||||||||||||
Homer1a | r=−0.236 | P=0.316 | r=0.221 | P=0.349 | r=0.286 | P=0.222 | r=0.224 | P=0.372 | r=−0.09 | P=0.723 | r=−0.051 | P=0.842 |
Homer1b/c | r=−0.116 | P=0.627 | r=0.253 | P=0.283 | r=0.060 | P=0.801 | r=0.191 | P=0.462 | r=0.422 | P=0.092 | r=0.414 | P=0.098 |
PSD95 | r=0.074 | P=0.764 | r=0.111 | P=0.652 | r=0.168 | P=0.491 | r=0.291 | P=0.226 | r =0.621** | P =0.005 | r =0.716** | P =0.001 |
Tamalin | r=−0.029 | P=0.905 | r=0.334 | P=0.150 | r=0.292 | P=0.212 | r=0.132 | P=0.591 | r =0.611** | P =0.005 | r =0.686** | P =0.001 |
