The first prospective, double-blind, randomized controlled study of acetylcysteine for the treatment of patients with non-acetaminophen-induced acute liver failure supports its use in patients in the early stages of liver failure. Emergency liver transplantation still has a fundamental role in the management of patients with the most severe form of this syndrome.
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Riordan, S., Williams, R. Management of non-acetaminophen-induced ALF. Nat Rev Gastroenterol Hepatol 7, 75–77 (2010). https://doi.org/10.1038/nrgastro.2009.236
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DOI: https://doi.org/10.1038/nrgastro.2009.236