Non-anatomical resection of colorectal liver metastases is the current preferred approach to maximize sparing of the hepatic parenchyma. A new study raises the question of whether resection in patients with KRAS-mutated colorectal liver metastases should be performed along segmental, anatomical lines to reduce the risk of local liver recurrence.
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The authors thank Ruth Haynes for help in preparing the manuscript.
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Brudvik, K., Vauthey, JN. KRAS mutations and hepatic recurrence after treatment of colorectal liver metastases. Nat Rev Gastroenterol Hepatol 14, 638–639 (2017). https://doi.org/10.1038/nrgastro.2017.129
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DOI: https://doi.org/10.1038/nrgastro.2017.129
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