Two recent reports in the American Journal of Transplantation focus on the maternal and fetal outcomes of pregnancies in kidney donors and provide tantalizing, if somewhat worrisome, observations. The findings also leave us with several important unanswered questions.
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References
Boudville, N. et al. Meta-analysis: risk for hypertension in living kidney donors. Ann. Intern. Med. 145, 185–196 (2006).
Garg, A. X. et al. Proteinuria and reduced kidney function in living kidney donors: a systematic review, meta-analysis, and meta-regression. Kidney Int. 70, 1801–1810 (2006).
Reisaeter, A. V., Roislien, J., Henriksen, T., Irgens, L. M. & Hartmann, A. Pregnancy and birth after kidney donation: the Norwegian experience. Am. J. Transplant. 9, 820–824 (2009).
Ibrahim, H. N. et al. Pregnancy outcomes after kidney donation. Am. J. Transplant. 9, 825–834 (2009).
Bellamy, L., Casas, J. P., Hingorani, A. D. & Williams, D. J. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ 335, 974 (2007).
Kajantie, E., Eriksson, J. G., Osmond, C., Thornburg, K. & Barker, D. J. Pre-eclampsia is associated with increased risk of stroke in the adult offspring: the Helsinki birth cohort study. Stroke 40, 1176–1180 (2009).
Fisher, K. A., Luger, A., Spargo, B. H. & Lindheimer, M. D. Hypertension in pregnancy: clinical-pathological correlations and remote prognosis. Medicine (Baltimore) 60, 267–276 (1981).
Buszta, C. et al. Pregnancy after donor nephrectomy. Transplantation 40, 651–654 (1985).
Jones, J. W., Acton, R. D., Elick, B., Granger, D. K. & Matas, A. J. Pregnancy following kidney donation. Transplant. Proc. 25, 3082 (1993).
Schaefer, G. & Markham, S. Full-term delivery following nephrectomy. Am. J. Obstet. Gynecol. 100, 1078–1086 (1968).
Wrenshall, L. E., McHugh, L., Felton, P., Dunn, D. L. & Matas, A. J. Pregnancy after donor nephrectomy. Transplantation 62, 1934–1936 (1996).
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Josephson, M. Pregnancy after kidney donation: more questions than answers. Nat Rev Nephrol 5, 495–497 (2009). https://doi.org/10.1038/nrneph.2009.129
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DOI: https://doi.org/10.1038/nrneph.2009.129
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