Arterial calcification is highly prevalent in patients with chronic kidney disease, and is a process associated with cardiovascular morbidity and mortality. Calcium phosphate deposits may be found in the intima, the media, or both. Whether determination of the precise location of calcification is possible and whether this distinction is clinically useful remains a matter of debate.
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Drüeke, T., Massy, Z. Medial or intimal calcification in CKD—does it matter?. Nat Rev Nephrol 7, 250–251 (2011). https://doi.org/10.1038/nrneph.2011.41
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DOI: https://doi.org/10.1038/nrneph.2011.41