MRI/ultrasonography (MRI/US)-fusion biopsy outperforms systematic ultrasonography-guided biopsy, detecting more high-grade prostate tumours while being less able to detect low-grade cancer, thus preventing overtreatment of indolent tumours. Any of several MRI-guided biopsy techniques has the potential, therefore, to replace systematic transrectal ultrasonography-guided prostate biopsies in the future.
Key Points
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MRI-guided biopsy is rapidly emerging as an alternative to systematic transrectal ultrasonography (TRUS)-guided biopsy for accurately detecting and localizing aggressive prostate cancers
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Different MRI-guided prostate biopsy methods include direct MRI-guided, MRI/US-fusion-guided, and cognitive-fusion-guided biopsy6
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In the future, MRI-guided biopsy will inevitably replace systematic TRUS-guided prostate biopsies
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Implementation of MRI/US-fusion-guided biopsies requires caution: good quality MR images and image interpretation is required, accurate segmentation and registration is essential for targeting tumour suspicious regions with MRI/US-fusion guidance, and small lesions have a chance of being missed using this technique
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Acknowledgements
The authors would like to thank Henk-Jan Huisman for assistance in discussion of content and contributions to writing this article.
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van de Ven, W., Barentsz, J. MRI/US-guided biopsy—a viable alternative to TRUS-guidance. Nat Rev Urol 10, 559–560 (2013). https://doi.org/10.1038/nrurol.2013.179
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DOI: https://doi.org/10.1038/nrurol.2013.179
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