Actophorin is a member of the actin-depolymerizing factor/cofilin family. It severs act in filaments and sequesters actin monomers. The crystal structure of actophorin will help to elucidate actin–ADF/cofilin interactions.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Pollard, T.D. & Cooper, J.A. Ann. Rev. Biochem. 55, 987–1035 (1986).
Moon, A. & Drubin, D.G. Mol. Biol. Cell. 6, 1423–1431 (1995).
Nishida, E. et al. J. Biochem. 95, 387–398 (1984).
Nishida, E. et al. Biochem. 23, 5307–5313 (1984).
Mabuchi, I. J. Cell Biol. 97, 1612–1621 (1983).
Cooper, J.A. et al. J. Biol. Chem. 261, 477–485 (1986).
lida, K. et al. Gene 124, 115–120 (1993).
Sutoh, K. & Mabuchi, I. Biochem. 25, 6186–6192 (1986).
Maneyuki, E. et al. J. Biochem. 97, 563–568 (1985).
Yonezawa, N. et al. J. Biol. Chem. 266, 10485–10489 (1991).
Yonezawa, N. et al. Eur. J. Biochem. 183, 235–238 (1989)
Yonezawa, N. et al. J. Biol. Chem. 260, 14410–144 (1985)
Yonezawa, N. et al. J. Biol. Chem. 265, 8382–8386 (1990)
Hayden, S.M. et al. Biochem. 32, 9994–10004 (1993)
Maciver, S.K. & Weeds, A.G. FEBS Letts 347, 251–256 (1991).
McLaughlin, P.J. et al. Nature 364, 685–692 (1993).
Hawkins, M. et al. Biochem. 32, 9985–9993 (1993).
Hatanaka, H. et al. Cell 85, 1047–1055 (1996).
Fedorov, A.A. et al. Nature Struct. Biol. 4, 366–369(1997)
Barton, G.J. ALSCRIPT. Prot. Engng. 6, 37–40 (1993).
Hutchinson, E.G. & Thornton, J. Prot. Sci. 3, 2207–2216 (1994).
Quirk, S. et al. Biochem. 32, 8525–8533 (1993).
Gewirth, D., Otwinowski, Z. & Wladek, M. The HKL Manual. (Yale University: 1994).
SERC Daresbury Laboratory. CCP4, a Suite of Programs for Protein Crystallography. (Warrington, UK: 1979).
Jones, T.A. et al. Acta crystallogr. A 47, 110–119 (1991).
Brunger, A.T. XPLOR (Version 3.1) manual (1992).
Kraulis, P.J. MOLSCRIPT J. Appl. Crystallogr. 24, 946–950 (1991).
Sayle, R. RasMol (Version 2.2): A Molecular Visualisation Program. (Univ. of Edinburgh, 1993).
Bairoch, A. & Apweiler, R. Nucl. Acids Res. 24, 21–25 (1996).
Nicholls, A. and Honig, B.J. GRASP. Comp. Chem. 12, 435–445 (1991).
Barton, G.J. & Sternberg, M.J.E. AMPS. J. Mol. Bio. 212, 389–402 (1990).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Leonard, S., Gittis, A., Petrella, E. et al. Crystal structure of the actin-binding protein actophorin from Acanthamoeba. Nat Struct Mol Biol 4, 369–373 (1997). https://doi.org/10.1038/nsb0597-369
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/nsb0597-369
This article is cited by
-
EhRab21 associates with the Golgi apparatus in Entamoeba histolytica
Parasitology Research (2020)
-
Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex
Nature Cell Biology (2001)
-
Structure determination of yeast cofilin
Nature Structural & Molecular Biology (1997)