A clutch of recent lipase structures lifts the lid on the mechanism of interfacial activation and the determinants of lipase substrate specificity
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$189.00 per year
only $15.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Brockman, H.L., Law, J.H., & Keady, F.J. J. biol. Chem. 248, 4965–4970 (1973).
Chapus, C., Semeriva, M., Bovier-Lapierre, C. & Desnuelle, P. Biochemistry, 15, 4980–4987 (1976).
Dennis, E.A. A2 . J. biol. Chem. 269, 13057–13060 (1994).
Brady, L. et al. Nature 343, 767–770 (1990).
Winkler, F.K., DÕArcy, A. & Hunziker, W. Nature 343, 771–774 (1990).
Derewenda, Z.S. & Sharp, A.M. Trends biochem. Sci. 18, 20–25 (1993).
Ollis, D.L. et al. Prot. eng. 5, 197–211 (1992).
Cygler, M. et al. Prot. Sci. 2, 366–382 (1993).
Derewenda, U. et al. J. Lipid Research 35, 524–534 (1994).
Grochulski, P. et al. J. biol. Chem. 268, 12843–12847 (1993).
Brozozowski, A.M. et al. Nature 351, 491–494 (1991).
Derewenda, Z.S., Derewenda, U. & Dodson, G.G. J. molec. Biol. 227, 818–839 (1992).
van Tilbeurgh, H. et al. Nature 362, 814–820 (1993).
Grochulski, P., Li, Y., Schrag, J.D. and Cygler, M. Prot. sci. 3, 82–91 (1994).
Cygler, M. et al. J. Am. chem. Soc. 16, 3180–3186 (1994).
Grochulski, P., Bouthillier, F., Kazlauskas, R.J., Serreqi A.N., Schrag, J.D., Ziomek, E. & Cygler, M. Biochemistry 33, 3493–3500 (1994).
Fischer, G., Bang, H., Berger, E., & Schellenber, A. Biochim. biophys. Acta 791, 87–97 (1984).
Lotti, M. et al. Gene 124, 45–55 (1993).
Kazlauskas, R.J., Weissflock, A.N.E., Rappaport, A.T. & Cuccia, L.A. J. org. Chem. 56, 2656–2665 (1991).
Brockerhoff, H. Biochim. biophys. Acta 159, 296–303 (1968).
Desnuelle, P., Sarda, L., & Aihaud, G. Biochim. biophys. Acta 37, 570–571 (1960).
Derewenda, U. Nature struct. Biol. 1, 36–47 (1994).
Brockman, H.L. in Lipases (eds Borgstrom, B. & Brockman, H.L.) 3–46 (Elsevier Science Publishers B.V. Amsterdam, 1984).
Muderhwa, J.M. & Brockman, J. biol. Chem. 267, 24184–24192 (1992).
Muderhwa, J.M. & Brockman J. biol. Chem. 265, 19644–19651 (1990).
Schrag, J.D., Li, Y., Wu, S. & Cygler, M. Nature 351, 761–764 (1991).
Noble, M.E.M. et al. FEBS letters 331, 123–128 (1993).
Uppenberg, J., Hansen, M.T., Patkar, S. & Jones, T.A. Structure 2, 293–308 (1994).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rubin, B. Grease pit chemistry exposed. Nat Struct Mol Biol 1, 568–572 (1994). https://doi.org/10.1038/nsb0994-568
Issue Date:
DOI: https://doi.org/10.1038/nsb0994-568
This article is cited by
-
Purification of lipase from Cunninghamella verticillata by stepwise precipitation and optimized conditions for crystallization
World Journal of Microbiology and Biotechnology (2005)
-
Purification and biochemical characterization of a novel thermostable lipase from Aspergillus niger
Lipids (2000)
-
Current state of the study of microbial lipases
Chemistry of Natural Compounds (1997)
-
Altered acyl chain length specificity of Rhizopus delemar lipase through mutagenesis and molecular modeling
Lipids (1997)